📋 Solublempnn

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design,

QUICK INSTALL
npx playbooks add skill adaptyvbio/protein-design-skills --skill solublempnn

About Solublempnn

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design,

This compact 39-word instruction set is purpose-built for developer workflow work in AI coding agents. Install with a single command.

Use Cases

  • Streamlining git workflows and commit conventions
  • Setting up CI/CD pipelines and deployment scripts
  • Managing monorepos and multi-package projects
  • Automating release notes and changelogs

Example Prompts

Get started Help me use the Solublempnn skill effectively.

System Prompt (39 words)

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design,

Frequently Asked Questions

What is Solublempnn?

Solublempnn is a free developer workflow skill for AI coding agents. Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, . It provides a specialized system prompt that configures your agent with developer workflow expertise.

How do I use Solublempnn with Claude Code?

Run npx playbooks add skill adaptyvbio/protein-design-skills --skill solublempnn in your terminal to install Solublempnn into your Claude Code session. It works immediately after installation.

Which AI coding agents work with Solublempnn?

Solublempnn is compatible with Claude Code, Cursor, GitHub Copilot, Windsurf, OpenClaw, Cline, and any AI agent that supports custom system prompts or .cursorrules files.

Is Solublempnn free to use?

Yes, Solublempnn is completely free and open source. The full source is available on GitHub at https://github.com/adaptyvbio/protein-design-skills/tree/main/skills/solublempnn. You only need a subscription to the AI agent you use it with.

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