Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote
npx playbooks add skill adaptyvbio/protein-design-skills --skill ligandmpnn
Ligandmpnn specializes your AI coding agent in developer workflow — it ligand-aware protein sequence design using ligandmpnn. use this skill when: (1) designing sequences around small molecules, (2) enzyme active site design, (3) ligand binding pocket optimization, (4) metal coordination site design, (5) cofactor binding proteins. for standard protein design, use prote.
At 41 words, this compact prompt gives your agent specialized developer workflow expertise with structured patterns and output formats. Install via CLI or copy the prompt below.
Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote
Ligandmpnn is a free developer workflow skill for AI coding agents. Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote. It provides a specialized system prompt that configures your agent with developer workflow expertise.
Run npx playbooks add skill adaptyvbio/protein-design-skills --skill ligandmpnn in your terminal to install Ligandmpnn into your Claude Code session. It works immediately after installation.
Ligandmpnn is compatible with Claude Code, Cursor, GitHub Copilot, Windsurf, OpenClaw, Cline, and any AI agent that supports custom system prompts or .cursorrules files.
Yes, Ligandmpnn is completely free and open source. The full source is available on GitHub at https://github.com/adaptyvbio/protein-design-skills/tree/main/skills/ligandmpnn. You only need a subscription to the AI agent you use it with.
Weekly roundup of top Claude Code skills, MCP servers, and AI coding tips.