📋 Ligandmpnn

Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote

QUICK INSTALL
npx playbooks add skill adaptyvbio/protein-design-skills --skill ligandmpnn

About Ligandmpnn

Ligandmpnn specializes your AI coding agent in developer workflow — it ligand-aware protein sequence design using ligandmpnn. use this skill when: (1) designing sequences around small molecules, (2) enzyme active site design, (3) ligand binding pocket optimization, (4) metal coordination site design, (5) cofactor binding proteins. for standard protein design, use prote.

At 41 words, this compact prompt gives your agent specialized developer workflow expertise with structured patterns and output formats. Install via CLI or copy the prompt below.

Use Cases

  • Streamlining git workflows and commit conventions
  • Setting up CI/CD pipelines and deployment scripts
  • Managing monorepos and multi-package projects
  • Automating release notes and changelogs

Example Prompts

Get started Help me use the Ligandmpnn skill effectively.

System Prompt (41 words)

Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote

Frequently Asked Questions

What is Ligandmpnn?

Ligandmpnn is a free developer workflow skill for AI coding agents. Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote. It provides a specialized system prompt that configures your agent with developer workflow expertise.

How do I use Ligandmpnn with Claude Code?

Run npx playbooks add skill adaptyvbio/protein-design-skills --skill ligandmpnn in your terminal to install Ligandmpnn into your Claude Code session. It works immediately after installation.

Which AI coding agents work with Ligandmpnn?

Ligandmpnn is compatible with Claude Code, Cursor, GitHub Copilot, Windsurf, OpenClaw, Cline, and any AI agent that supports custom system prompts or .cursorrules files.

Is Ligandmpnn free to use?

Yes, Ligandmpnn is completely free and open source. The full source is available on GitHub at https://github.com/adaptyvbio/protein-design-skills/tree/main/skills/ligandmpnn. You only need a subscription to the AI agent you use it with.

Related Skills

Get the best new skills
in your inbox

Weekly roundup of top Claude Code skills, MCP servers, and AI coding tips.