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📋 Ligandmpnn

Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote

QUICK INSTALL
npx playbooks add skill adaptyvbio/protein-design-skills --skill ligandmpnn

About

Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote. This skill provides a specialized system prompt that configures your AI coding agent as a ligandmpnn expert, with detailed methodology and structured output formats.

Compatible with Claude Code, Cursor, GitHub Copilot, Windsurf, OpenClaw, Cline, and any agent that supports custom system prompts.

Example Prompts

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System Prompt (41 words)

Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use prote

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